Would Using Sub Domains Instead Of Inner Pages Rule Out Using Silos?

In episode 182 of Semantic Mastery's weekly Hump Day Hangouts, one participant asked if using subdomains instead of inner pages rules out using silos.

The exact question was:

You explained why it is better to use sub-domains instead of “”inner pages”” for each geo location on a local lead gen site, but would doing so rule out using “”silos””?

Thank you VERY much again for your help

Sincerely,
Gordon